发表论文

2024

 1)  Yan Bai, Duo Ren, Xinlei Xue, Weixian Gao, Jiangchun Hu, and Huaqi Pan*. Structurally diverse brefeldin A derivatives as potent and selective acetylcholinesterase inhibitors from an endophytic fungus Penicillium brefeldianum F4a. Arabian Journal of Chemistry, 2024, 17, 105388. 

2023年

 1) Yan Bai, Duo Ren, Fenglin Li, Jiangchun Hu, Huaqi Pan*. Genome mining and molecular networking guided isolation of antimycin analogues with antifeedant activities from the deep-sea-derived Streptomyces sp. NA13. Chemistry & Biodiversity, 2023, 20, e202300715. 

 2) Wang Mingying, Sun Baojia, Ye Tao, Wang Yanbing, Hou Yonglian, Wang Siyuan, Pan Huaqi, Hua Huiming*, Li Dahong*. 5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione derivatives of brefeldin A: Design, synthesis and cytotoxicity in MDA-MB-231 human breast cancer cells. Bioorganic & Medicinal Chemistry. 2023, 90, 117380. 

 3) Wang Mingying, Chen Xiaoyuan, Qu Ying, Ma Qingyinglu, Pan Huaqi, Li Haonan, Hua Huiming*, Li Dahong*. Design and synthesis of brefeldin A-isothiocyanate derivatives with selectivity and their potential for cervical cancer therapy. Molecules. 2023, 28, 4284

 4) 刘晶莹, 白岩, 潘华奇, 胡江春*. 卡伍尔氏链霉菌NA4的 型聚酮基因簇的靶向激活及其产物鉴定. 微生物学报. 2023, 63 (10): 3891-3904.

 

2022

 1) Yan Bai, Ping Yi, Fenglin Li, Jiangchun Hu, Huaqi Pan*. Penipentenone A and brefeldin A derivatives potently inhibit KRAS mutant cancer cells from an endophytic fungus Penicillium brefeldianum F4a. Phytochemistry, 2022, 200: 113243.

 2) Xueying Xie, Zexi Zhao, Hetong Yang, Huaqi Pan, Changxiang Zhu, Jiangchun Hu, Yan Bai*. Nigirpexin E, a new azaphilone derivative with anti-tobacco mosaic virus activity from soil-derived fungus Trichoderma afroharzianum LTR-2. The Journal of Antibiotics, 2022, 75 (2), 117-121.

 3) 潘华奇*. 后基因组时代微生物天然产物高效发掘体系设计与展望, 微生物学杂志. 2022, 42 (3):1-14(大家专版邀稿). 

 4) 鲍秀艳, 姚雪春, 史美君, 胡江春, 潘华奇*. 卡伍尔氏链霉菌NA4生物合成巴弗洛霉素前体甲氧基丙二酰ACP来源的研究, 微生物学杂志. 2022,42 (1):9-16.

 5) 石逸冰, 白岩, 潘华奇, 胡江春*. 植物内生真菌F4a 次级代谢产物的分离鉴定以及降血糖、抗氧化活性的研究. 微生物学杂志. 2022,42(2):26-30.

 

2021

 1)  Yan Bai, Ping Yi, Songya Zhang, Jiangchun Hu, Huaqi Pan*. Novel antioxidants and -glycosidase and protein tyrosine phosphatase 1B inhibitors from an endophytic fungus Penicillium brefeldianum F4a. Journal of Fungi, 2021, 7, 913.

 2)  Yan Bai, Ping Yi, Yun Zhang, Jiangchun Hu, Ying Wang, Jianhua Ju, Huaqi Pan*. Structure-based molecular networking for the target discovery of novel germicidin derivatives from the sponge-associated streptomyces sp. 18A01. The Journal of Antibiotics, 2021, 74 (11), 799-806. (Highlighted article) .

3)  Xiaoying Zhang, Chunfeng Song, Yan Bai, Jiangchun Hu, Huaqi Pan*. Cytotoxic and antimicrobial activities of secondary metabolites isolated from the deep?sea?derived Actinoalloteichus cyanogriseus 12A22. 3 Biotech, 2021, 11: 283.

2020年前(部分论文)

1)     Ma Zongwang*, Zhang Songya, Liang Junyu, Sun Kun, Hu Jiangchun*. Isolation and characterization of a new cyclic lipopeptide orfamide H from Pseudomonas protegens CHA0, J. Antibiot., 2020,73(3)179-183.

2)     Ma Zongwang*, Zhang Songya, Zhang Shihu, Wu Guoyang, Shao Yue, Mi Quanfeng, Liang Junyu, Sun Kun, Hu Jiangchun*. Isolation and characterization of a new cyclic lipopeptide surfactin from a marine-derived Bacillus velezensis SH-B74, J. Antibiot., 2020, 73863-867.

3)     Pan Hua-Qi, Tian Xin-Peng, Shao Ming-Wei, Xie Yun-Chang, Huang Hong-Bo, Hu Jiang-Chun, Ju Jian-Hua*, Genome mining and metabolic profiling illuminate the chemistry driving diverse biological activities of Bacillus siamensis SCSIO 05746. Appl. Microbiol. Biot. 2019, 103(10):4153-4165.

4)     Ma Zongwang*, Zhang Songya, Sun Kun, Hu Jiangchun*. Identification and characterization of a cyclic lipopeptide iturin A from a marine-derived Bacillus velezensis 11-5 as a fungicidal agent to Magnaporthe oryzae in rice, J. Plant. Dis. Prot., 2019, 127(1): 15-24

5)     Ma Zongwang, Hu Jiangchun*. Plipastatin A1 produced by a marine sediment-derived Bacillus amyloliquefaciens SH-B74 contributes to the control of gray mold disease in tomato3 Biotech20188: 125.

6)     Ma Zongwang, Hu Jiangchun*. Complete genome sequence of a marine-sediment-derived bacterial strain Bacillus velezensis SH-B74, a cyclic lipopeptides producer and a biopesticide3 Biotech, 2019, 9: 162.

7)     Han Tong#, Tian Kang-Tao#, Pan Hua-Qi#, Liu Yong-Xiang, Xu Fan-Xing, Li Zhan-Lin, Uchita Takahiro, Gao Ming, Hua Hui-Ming, Li Da-Hong*. Novel hybrids of brefeldin A and nitrogen mustards with improved antiproliferative selectivity: Design, synthesis and antitumor biological evaluation. Eur. J. Med. Chem. 2018, 150:53-63.

8)     Pan Hua-Qi, Li Qing-Lian, Hu Jiang-Chun*. The complete genome sequence of Bacillus velezensis 9912D reveals its biocontrol mechanism as a novel commercial biological fungicide agent. J. Biotechnol. 2017, 247: 25-28.

9)     Tian Kang-Tao#, Xu Fan-Xing#, Gao Xiang, Han Tong, Li Jia, Pan Hua-Qi*, Zang Ling-He, Li Da-Hong*, Li Zhan-Lin, Uchita Takahiro, Gao Ming, Hua Hui-Ming*. Nitric oxide-releasing derivatives of brefeldin A as potent and highly selective anticancer agents. Eur. J. Med. Chem. 2017,136:131-143.

10)  Pan Hua-Qi, Yu Su-Ya, Song Chun-Feng, Wang Nan, Hua Hui-Ming, Hu Jiang-Chun*, Wang Shu-Jin. Identification and characterization of the antifungal substances of a novel Streptomyces cavourensis NA4. J. Microbiol. Biotechnol. 2015. 25 (3): 353-357.

11)  Pan Hua-Qi, Cheng Juan, Zhang Dao-Feng, Yu Su-Ya, Khieu Thi-Nhan, Son Chu Ky, Jiang Zhao, Hu Jiang-Chun*, Li Wen-Jun*. Streptomyces bohaiensis sp. nov., a novel actinomycete isolated from Scomberomorus niphonius in the Bohai Sea. J. Antibiot. 2015.68 (4): 246-252.

12)  Pan Hua-Qi #, Zhang Dao-Feng#, Li Li, Jiang Zhao, Cheng Juan, Zhang Yong-Guang, Wang Hong-Fei, Hu Jiang-Chun*, Li Wen-Jun*. Nocardiopsis oceani sp. nov. and Nocardiopsis nanhaiensis sp. nov., two novel actinomycete isolated from marine sediment of South China Sea, Int. J. Syst. Evol. Microbiol. 2015 65: 3384-3391.

13)  Pan Hua-Qi *, Hu Jiang-Chun *. Draft genome sequence of the novel strain Pseudomonas sp. 10B238 with potential ability to produce antibiotics from deep-sea sediment. Mar. Genom. 2015. 23: 55-57.

14)  Chen Xiaoqi, Mou Yanhua, Ling Junhong, Wang Nan*, Wang Xiao, Hu JiangchunCyclic dipeptides produced by fungus Eupenicillium brefeldianum HMP-F96 induced extracellular alkalinization and H2O2 production in tobacco cell suspensionsWorld J. Microbiol. Biotechnol., 2015, 31(1):247-253.

15)  Ma Zongwang, Hu Jiangchun*. Production and characterization of surfactin-type lipopeptides as bioemulsifiers produced by a Pinctada martensii-derived Bacillus mojavensis B0621A, Appl. Biochem. Biotechnol., 2015, 177(7): 1520-1529.

16)  Ma Zongwang, Hu Jiangchun*, Wang Xuemei, Wang Shujin. NMR spectroscopic and MS/MS spectrometric characterization of a new lipopeptide antibiotic bacillopeptin B1 produced by a marine sediment-derived Bacillus amyloliquefaciens SH-B74J. Antibiot., 201467(2):175-8

17)  Ma Zongwang, Hu Jiangchun*. Production and characterization of iturinic lipopeptides as antifungal agents and biosurfactants produced by a marine Pinctada martensii-derived Bacillus mojavensis B0621AAppl. Biochem. Biotechnol.2014, 173:705-715

18)  Pan, Hua-Qi, Zhang Song-Ya, Wang Nan, Li Zhan-Lin, Hua Hui-Ming, Hu Jiang-Chun*, Wang, Shu-Jin. New spirotetronate antibiotics, lobophorins H and I, from a South China Sea-derived Streptomyces sp. 12A35. Mar. Drugs. 2013. 11: 3891-3901.

19)  Zhang Dao-Feng #, Pan Hua-Qi #, He Jie, Zhang Xiao-Mei, Zhang Yong-Guang, Klenk Hans-Peter, Hu Jiang-Chun*, Li Wen-Jun*. Description of Streptomonospora sediminis sp. nov. and Streptomonospora nanhaiensis sp. nov., and reclassification of Nocardiopsis arabia (Hozzein & Goodfellow, 2008) as Streptomonospora arabica comb. nov. and emended description of the genus Streptomonospora. Int. J. Syst. Evol. Microbiol. 2013. 64: 4447-4455.

20)  Ma Zongwang, Wang Nan, Hu Jiangchun*, Wang Shujin. Isolation and characterization of a new iturinic lipopeptide, mojavensin A produced by a marine-derived bacterium Bacillus mojavensis B0621A, J. Antibiot., 2012,65:317-322.

21)  Zhao Li, Liu Li, Wang Nan, Wang Shu-Jin, Hu Jing-Chun*, Gao Jin-Ming*. Potent toxic macrocyclic trichothecenes from the marine-derived fungus Myrothecium verrucaria Hmp-F73Natural Product Communications ,2011, 6(12): 1915-1916.

22)  Chen Lili, Wang Nan, Wang Xuemei, Hu Jiangchun*, Wang Shujin. Characterization of two antifungal lipopeptides produced by Bacillus amyloliquefaciens SH-B10,Bioresour. Technol., 2010,101(22): 8822-8827.

23)  Liu Li, Duan Zhenghu, Xu Mingkai,Hu Jiangchun*, Wang Silong, Zhang Qianru, Hu Zhigang,Wang Shujin. Effect of monospecific and mixed Cunninghamia lanceolata plantations on microbial community and two functional genes involved in nitrogen cycling, Plant and Soil, 2010, 327413-428.

24)  Pan Hua-Qi, Wang Nan, Liu Lie, Liu, Li, Hu Jiang-Chun, Chen Pu-Yan, Wang Shu-Jin, Cao Rui-Bing*. Molecular characterization of the duck enteritis virus UL4 gene. Virologica Sinica 2009. 24: 171-178.

25)  Pan Hua-Qi, Cao Rui-Bing*, Liu Lie, Niu Ming-Fu, Zhou Bin, Chen Pu-Yan, Hu Jiang-Chun. Molecular cloning and sequence analysis of the duck enteritis virus UL5 gene. Virus Research 2008. 136: 152-156.

26)  Lixin Zhang, Rong An, Jinping Wang, Nuo Sun, Si Zhang, Jiangchun Hu and Jun Kuai, Exploring novel bioactive compounds from marine microbes, Current Opinion in Microbiology, 8(3), 276-281.